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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
E2F8
All Species:
5.45
Human Site:
S613
Identified Species:
15
UniProt:
A0AVK6
Number Species:
8
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
A0AVK6
NP_078956.2
867
94166
S613
R
A
S
M
L
E
D
S
G
S
K
K
K
F
K
Chimpanzee
Pan troglodytes
XP_508325
867
94169
S613
R
A
S
M
L
E
D
S
G
S
K
K
K
F
K
Rhesus Macaque
Macaca mulatta
XP_001095088
867
94195
G613
R
A
S
M
L
E
D
G
G
S
K
K
K
F
R
Dog
Lupus familis
XP_534087
864
93661
E610
S
K
R
A
S
T
L
E
D
G
G
S
K
K
K
Cat
Felis silvestris
Mouse
Mus musculus
Q58FA4
860
93258
G606
M
I
T
A
E
D
S
G
P
S
S
V
K
K
P
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506156
878
95490
N624
R
S
N
V
L
E
D
N
T
S
I
K
K
F
K
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001084876
724
79575
L471
Y
C
Q
A
F
P
L
L
Q
H
H
P
N
T
A
Zebra Danio
Brachydanio rerio
XP_694311
917
100437
E664
Q
T
G
T
A
S
L
E
H
S
L
E
T
F
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002321561
384
43173
S131
D
E
D
D
D
S
D
S
N
P
N
T
G
S
Q
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
96.6
89.6
N.A.
83
N.A.
N.A.
73.8
N.A.
48
39.3
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.3
98.1
94.2
N.A.
88.5
N.A.
N.A.
82.1
N.A.
59.9
55.4
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
86.6
13.3
N.A.
13.3
N.A.
N.A.
60
N.A.
0
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
93.3
13.3
N.A.
26.6
N.A.
N.A.
86.6
N.A.
0
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
20.3
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
30.1
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
20
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
34
0
34
12
0
0
0
0
0
0
0
0
0
12
% A
% Cys:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
12
0
12
12
12
12
56
0
12
0
0
0
0
0
0
% D
% Glu:
0
12
0
0
12
45
0
23
0
0
0
12
0
0
0
% E
% Phe:
0
0
0
0
12
0
0
0
0
0
0
0
0
56
0
% F
% Gly:
0
0
12
0
0
0
0
23
34
12
12
0
12
0
0
% G
% His:
0
0
0
0
0
0
0
0
12
12
12
0
0
0
0
% H
% Ile:
0
12
0
0
0
0
0
0
0
0
12
0
0
0
0
% I
% Lys:
0
12
0
0
0
0
0
0
0
0
34
45
67
23
45
% K
% Leu:
0
0
0
0
45
0
34
12
0
0
12
0
0
0
12
% L
% Met:
12
0
0
34
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
12
0
0
0
0
12
12
0
12
0
12
0
0
% N
% Pro:
0
0
0
0
0
12
0
0
12
12
0
12
0
0
12
% P
% Gln:
12
0
12
0
0
0
0
0
12
0
0
0
0
0
12
% Q
% Arg:
45
0
12
0
0
0
0
0
0
0
0
0
0
0
12
% R
% Ser:
12
12
34
0
12
23
12
34
0
67
12
12
0
12
0
% S
% Thr:
0
12
12
12
0
12
0
0
12
0
0
12
12
12
0
% T
% Val:
0
0
0
12
0
0
0
0
0
0
0
12
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
12
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _